RiteMED Clopidogrel Adverse Reactions

As with all drugs which may affect hemostasis, bleeding is associated with clopidogrel. Hemorrhage may occur at virtually any site. Risk is dependent on multiple variables, including the concurrent use of multiple agents which alter hemostasis and patient susceptibility. Other adverse effects are as follows: Gastrointestinal: Abdominal pain, vomiting, nausea, dyspepsia, gastritis, diarrhea, constipation, GI hemorrhage, pancreatitis, stomatitis.
Cardiovascular: Chest pain, edema, hypertension, atrial fibrillation, cardiac failure, palpitation, syncope, angioedema, vasculitis.
Central Nervous System: Headache, dizziness, depression, fatigue, general pain, fever, insomnia, vertigo, anxiety, hemorrhagic stroke, intracranial hemorrhage, confusion, hallucination.
Dermatologic: Rash (severe, maculopapular), pruritus, eczema, allergic reaction, anaphylactoid reaction, bullous eruption, urticaria, erythema multiforme, lichen planus, Stevens Johnson syndrome, toxic epidermal necrolysis.
Endocrine-Metabolic: Hypercholesterolemia, gout, hyperuricemia, pancreatitis.
Immunologic: Serum sickness.
Genitourinary: Urinary tract infection, cystitis, hematuria.
Hematologic: Bleeding, thrombotic thrombocytopenic purpura (TTP), epistaxis, hematoma, anemia, agranulocytosis, bilirubinemia, granulocytopenia, hypochromic anemia, neutropenia, leukopenia, thrombocytopenia, aplastic anemia, retroperitoneal bleeding, pancytopenia.
Hepatic: Liver function test abnormalities, fatty liver, acute liver failure, hepatitis.
Neuromuscular and skeletal: Arthralgia, back pain, arthritis, leg cramps, neuralgia, paresthesia, weakness.
Respiratory: Dyspnea, rhinitis, bronchitis, cough, upper respiratory infection, bronchospasm, hemoptysis, hemothorax, pulmonary hemorrhage, interstitial pneumonitis.
Ocular: Cataract, conjunctivitis, ocular hemorrhage.
Miscellaneous: Flu-like syndrome, ischemic necrosis, menorrhagia; hypersensitivity, taste disorder.